IMAGE

Figure 7

ID
ZDB-IMAGE-211002-94
Source
Figures for Chen et al., 2021
Image
Figure Caption

Figure 7

Heteronemin suppressed the migration and endothelial-to-mesenchymal transition of human lymphatic endothelial cells. Cells were treated with the indicated concentrations of heteronemin (represented as SP-1). (A) Cell migration was examined by Transwell assays (scale bar=100 µm; magnification ×100). (B) The quantification of migration was performed using Image-J to validate the anti-lymphangiogenic function of SP-1. (C) LECs were treated with SP-1. Then, the expression of ARF-1 and endothelial-mesenchymal transition-related proteins (MMP-9, VE-cadherin and vimentin) was determined by Western blot analysis. (D) The quantitative densitometry of the relative levels of ARF-1, MMP-9, VE-cadherin and vimentin was measured by Image-Pro Plus. Data are expressed as the mean ± SEM of at least three independent experiments. * p < 0.05, # p < 0.01 compared with the control group.

Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Biomedicines