ZFIN Image: Linder et al., 2021, Figure 8

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Figure Caption

Figure 8

Reduced stemness of the GSC cultures GS-5, NCH644 and the primary culture 17/02. Log-fraction plot of the limited dilution model of data from (A) GS-5, (B) NCH644 GSCs and (C) the primary culture 17/02 treated with solvent (DMSO, black), the IC₂₅ (red) and IC₅₀ (green) of 1a and the IC₂₅ (dark blue) or IC₅₀ (light blue) of 1b for 10 days and analyzed using ELDA software [18]. The data are the summary of 2 experiments performed in 12 replicates (n = 24 per group). *: p < 0.05; **: p < 0.01; ****: p < 0.0001; Pairwise Test for Differences using Chi-square-test (ELDA). The estimated stem-cell frequency (number of cells needed to form a sphere) is given in Table 3.

Acknowledgments

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