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FIGURE 5
The workflow of systematic processes to identify key synergy-mediated players. Step 1: Choosing the natural compound pair from the natural compounds library. Step 2: Obtaining DEGs from transcriptomics or proteomics profiling. Step 3: Mapping DEGs to cancer signaling transduction networks. Step 4: Inferring key synergy-mediating targets among DEGs based on network topology and empirical experience. Step 5: Validating suspected targets through
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Full text @ Front Cell Dev Biol