IMAGE

Fig 1

ID
ZDB-IMAGE-210729-7
Source
Figures for Kowalewski et al., 2021
Image
Figure Caption

Fig 1 Schematic representation of the domain organization of the 12 human CEACAM receptors and of zebrafish CEACAMz1.

Immunoglobulin domains composing the CEACAM ectodomains are displayed as oval spheres (in red for Ig-V domains; in light or dark grey for A-type or B-type Ig-C2 domains, respectively). Single-pass transmembrane helices are represented by blue, rounded rectangles. GPI anchors are shown in cyan. Cytoplasmic ITIM (Immunoreceptor Tyrosine-based Inhibitory Motif) and ITAM-like (Immunoreceptor Tyrosine-based Activation Motif) motifs are highlighted in green and orange, respectively. Purple arrows indicate the CEACAMs for which several isoforms have been characterized.

Acknowledgments
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