ZFIN Image: Noy-Lotan et al., 2021, Fig. 3

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Figure Caption

Fig. 3

Cdan^ΔEry erythroblasts display the pathognomonic spongy heterochromatin of CDA type I. (A) TEM of E9.5 (upper panel) and E11.5 (lower panel) Cdan^ΔEry erythroblasts compared to littermate controls. Magnification: X6000-9900. Scale bar: 1–2 μm. (B) High power magnification (X20,000-43,000) of E9.5 erythroblasts in A, showing the normal appearance of heterochromatin and the intact nuclear membrane in control erythroblast (left), compared to Cdan^ΔEry erythroblast with spongy heterochromatin, dilated membrane pore (arrow) and ribosomes (R) inside the nucleus. Scale bar: 500 nm.

Acknowledgments

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