ZFIN Image: Zhou et al., 2021, Figure 2<tag0:x xml:space='preserve'>. </tag0:x>

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Figure Caption

Figure 2.

Association between RBC hypoperfusion and vessel regression in the developing retinal network. (a) Classification of vessels based on their ICAM2 and Col.IV signals (here demonstrating ROI-1 as in figure 1a). All vessels in the ROI are divided into three groups, i.e. lumenized, regression and stenosis. (b) A snapshot of the simulation of RBC flow in ROI-1. (c) Combined cell trajectories in ROI-1 throughout the simulation (over 0.49 s). (d–g) Statistical test of time-average RBC flux for the mentioned three groups in ROI-1, ROI-2, ROI-3 and ROI-4, respectively. Two-sided Mann–Whitney U test is performed. The sample sizes for the three groups are n = 44, 6, 13 in (d); n = 16, 3, 4 in (e); n = 18, 4, 6 in (f); n = 19, 7, 4 in (g).

Acknowledgments

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