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Publication: Swartz et al., 2021 - Variation in phenotypes from a Bmp-Gata3 genetic pathway is modulated by Shh signaling
All Figures: Figures for Swartz et al., 2021

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Fig 1 A null allele of <italic toggle='yes'>gata3</italic> generated via CRISPR-Cas9.

(A) As previously reported gata3^b1075 mutation is located in exon 4. The CRISPR gata3 mutant allele au42 disrupts the second exon. (B) The gata3 au42 allele is a two base pair insertion/25 base pair deletion. (C) Predicted wild type and gata3^au42 mutant protein sequences indicates a frame shift followed by four consecutive stops in translation.

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