ZFIN Image: Liao et al., 2021, FIGURE 2

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FIGURE 2

ADQ attenuates the proliferation, self-renewal and differentiation of breast CSCs. (A) ADQ administration for 48 h could remarkably reduce the proportions of CD44⁺CD24^−/low subsets in both the MDA-MB-231 cells and MCF-7 cells. (B) 50 μg/ml ADQ with or without 50 nM taxol markedly limited the numbers and sizes of the primary and secondary mammospheres. (C) ADQ treatment dramatically attenuated the differentiation ability of breast CSCs. All values represent the means ± SD (n = 3, *p < 0.05, **p < 0.01 vs. Control group; ^#p < 0.05, ^##p < 0.01 vs. Taxol group).

Acknowledgments

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