ZFIN Image: Wang et al., 2021, FIGURE 7

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FIGURE 7

Tumor volume and angiogenesis were inhibited by engineered RGD‐SKOV3‐92b/exo alone or combined with Apatinib. (A) Gross anatomy images of nude mice in the peritoneal cavity. (B) Schematic representation of intraperitoneal xenografted tumors in different groups. Tumor size from each group was measured and weighed as represented. (C) Immunohistochemical staining of CD31 in intraperitoneal xenografted tumors (scale bar = 100 μm and 50 μm). Micro‐vessels density (MVD) was assessed by counting CD31‐positive cells (n = 5). Data are shown by at least three independent experiments. The Student's t‐test and nonparametric test were used to compare differences. *p < .05, **p < .01, ***p < .001, ****p < .0001

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