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Publication: Shimizu et al., 2021 - Transcriptome Analyses Reveal IL6/Stat3 Signaling Involvement in Radial Glia Proliferation After Stab Wound Injury in the Adult Zebrafish Optic Tectum
All Figures: Figures for Shimizu et al., 2021

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FIGURE 2

Induction of IB4+ macrophage migration during the early stages after stab wound injury. (A–D) Representative images of IB4-positive macrophages in intact fish (A) and the injured hemisphere of injured fish during the early stages of regeneration, 6, 12, and 24 hpi (B–D). (A’–D’) Magnified images of the boxed area in each image. White arrowheads indicate BLBP+ PCNA+ cells and dashed lines (B–D) indicate the area injured by needle insertion. Scale bar: 100 μm in (A–D), 50 μm in (A’–D’). (E) Quantification of IB4-positive cells in intact fish (n = 4) and the uninjured and injured hemispheres of injured fish at 6, 12, and 24 hpi. Statistical analyses between uninjured and injured hemispheres at each time point were evaluated using paired Student’s t-tests.

Acknowledgments

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