ZFIN Image: Ko et al., 2021, Figure 6

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Figure Caption

Figure 6 Modulation of TMEM16A(ac) channels by the M₁ muscarinic receptor (M₁R). (A) Representative C^l? current traces of TMEM16A(ac) before and after application of the M1R agonist oxotremorine-M (Oxo-M). Whole-cell recordings were measured before (t₀, black) and 200 s after (t₂₀₀, gray and red) the application of 10 ?M Oxo-M in cells co-transfected without (left) and with (right) M1R. Cells were dialyzed with an intracellular solution including 10 mM EGTA and zero Ca²⁺, and the current was measured at +100 mV every 5 s. (B) Normalized mean current � SEM. TMEM16A(ac), n = 5; TMEM16A(ac) + M1R, n = 5.

Acknowledgments

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