ZFIN Image: Wright et al., 2021, Fig 6

Image

Figure Caption

Fig 6 Cxcl12a knockdown places the Cxcl12/Cxcr4 signalling axis downstream of miR-206.

(A) Whole body neutrophil counts at 3 dpi of cxcl12a and double (cxcl12a and miR-206) knockdown embryos. (B) Measurement of neutrophil recruitment to M. marinum following trunk injection in double knockdown embryos. (C) Bacterial burden at 3 dpi in M. marinum-infected double knockdown embryos. Each data point represents a single measurement, with the mean and SEM shown. For time-lapse imaging, each data point represents the mean of 4 foci of infection from 4 separate embryos. Bacterial burden analysis was performed on 20–30 embryos per treatment. Graphs are representative of 2 biological replicates.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Pathog.