ZFIN Image: Lai et al., 2021, Figure 7

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Figure Caption

Figure 7 The anti-inflammatory effect of compounds in the chemically induced inflammation model. The time of image acquisition was when Tg(mpx:GFP) zebrafish larvae develop to 56 hpf. Currently, transgenic zebrafish larvae exhibit green fluorescent leukocytes. Untreated fish (control) show the normal distribution of labeled cells, mostly localized in the ventral trunk and tail. In copper-treated siblings (50 μM CuSO₄), leukocytes become localized preferentially to a few clusters along the horizontal midline of the trunk and tail (see white arrows); no overt tissue damage to the larvae is observed in bright-field images., and relieving inflammation by applying aspirin (20 μM) as a positive standard. Before treated with CuSO₄, zebrafish larvae were incubated with butin and caffeic acid [1, 10, 100] μM.

Acknowledgments

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