IMAGE

Fig. 9

ID
ZDB-IMAGE-210331-21
Publication
Zhong et al., 2021 - Bmp8a is an essential positive regulator of antiviral immunity in zebrafish
All Figures
Figures for Zhong et al., 2021
Image
Figure Caption

Fig. 9 Schematic illustration of Bmp8a serving as positive regulator in the antiviral immune.

Upon virus infection, the transcriptions of bmp8a are activated through the Jak-Stat1 pathway. The Bmp8a binds to BMP type I receptor Alk6a, promoting phosphorylation of Tbk1 and Irf3 to induce the expression of Ifn through p38 MAPK pathway.

Acknowledgments
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