FIGURE 5

FIGURE 5

Anti-epileptic effect of mAb against second hit PTZ-induced seizures. Seizure scores of corresponding experimental groups are demonstrated for day 10. Data are represented as mean ± SEM, n = 12, and statistically analyzed by one-way ANOVA followed by Sidak’s multiple comparison test. ^&&&&p < 0.0001, ****p < 0.0001 and ^##p < 0.01 represent the significance level when second hit PTZ group is compared with VC group, Pilo group and PTZ group, respectively. ^$$$p < 0.001 and ^$$p < 0.01 represents the significance level when DZP, mAb 1, mAb 2.5, and mAb 5 treated groups is compared with second hit PTZ group.