FIGURE 4

FIGURE 4

Mean locomotor parameters of the experimental groups (n = 12) at day 10. Mean locomotion parameters of the experimental groups representing the mean total distance traveled (cm) (A), mean time spent in upper half of the tank in (seconds) (B) and the mean time spent in lower half of the tank (seconds) (C). Data are represented as mean ± SEM, n = 12, and statistically analyzed by one-way ANOVA followed by Sidak’s multiple comparison test. ^&&&p < 0.001 and ^&&p < 0.01 represent the significance level when second hit PTZ group is compared with VC group. ***p < 0.001 and **p < 0.01 represent the significance level when second hit PTZ group is compared with Pilo group. ^$$p < 0.01 and ^$p < 0.05 represents the significance level when DZP, mAb 1, mAb 2.5, and mAb 5 treated groups is compared with second hit PTZ group.