IMAGE
Fig. 4
- ID
- ZDB-IMAGE-210303-78
- Publication
- Dapueto et al., 2020 - A novel nitroalkene vitamin E analogue inhibits the NLRP3 inflammasome and protects against inflammation and glucose intolerance triggered by obesity
- All Figures
- Figures for Dapueto et al., 2020
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Figure Caption
Fig. 4 Fig. 4. NATx0 inhibits acute NLRP3 activation and IL-1β production in vivo. C57BL/6 mice were injected intraperitoneally (i.p) with 20 mg/kg NATx0 or vehicle (DMSO) 1 h before i.p. injection of 10 mg/kg LPS Escherichia coli or PBS. After 2 h mice were killed and levels of IL-1β in serum and peritoneum was measured by ELISA. One-way ANOVA with Bonferroni's multiple comparison test: *** <0.0001; **** <0.0001; ** = 0.0004 (n = 7 per group).
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