ZFIN Image: Crespo et al., 2021, Fig. 7

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Figure Caption

Fig. 7 Schematic illustration showing the endocrine and paracrine regulation of zebrafish Insl3 and the stages of spermatogonial development affected.

Described effects are indicated by black (Fsh), gray (Insl3), blue (Pparg), and orange (RA) arrows, while germ cell development or germ cell-mediated effects are indicated in green. Gray dashed line denotes no experimental evidence reported. Fsh, follicle-stimulating hormone; Insl3, insulin-like 3; Pparg, peroxisome proliferator-activated receptor gamma; RA, retinoic acid; Cx43, connexin 43; Rxfp2a, relaxin family peptide receptor 2a; Rxfp2b, relaxin family peptide receptor 2b; A_und, type A undifferentiated spermatogonia; A_diff, type A differentiating spermatogonia; B, type B spermatogonia; SPC, spermatocytes; SPT, spermatids; SPZ, spermatozoa; Leydig, Leydig cell; Sertoli, Sertoli cell.

Acknowledgments

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