|
Fig. 3 Gonadal hypertrophy in bmpr2a mutant. (A) Ovaries of different genotypes at 5 mpf. The bmpr2a mutation (bmpr2a−/−) caused significant enlargement of the ovary, which contained a large number of PG follicles, with only a few entering PV and vitellogenic growth. (B) Testes of different genotypes at 5 mpf. The bmpr2a mutation also induced hypertrophic growth of the testis, which contained abundant spermatogonia with limited meiosis. (C) Body length, body weight and GSI of different genotypes (n=5; *P<0.05, **P<0.01; two-tailed Student's t-test for unpaired data). (D) Sex ratios in different genotypes. SC, spermatocytes; SG, spermatogonia; ST, spermatids; SZ, spermatozoa. Arrows indicate ovaries or testes.