ZFIN Image: Fish et al., 2021, Figure 8

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Figure 8 Fluorescent thrombocyte binding and aggregation after PCV laser injury in fga^−/− larvae with transgenic AαE or AαE R28C expression: a model of dysfibrinogenemia. (A) A scheme representing the experimental setup. Early Tg(itga2b:EGFP), fga^−/− embryos were microinjected with Tol2 transgenesis plasmids for expression of fibrinogen AαE or AαE R28C, AαE + AαE R28C or a half quantity of AαE (AαE ½). Tol2 transposase mRNA was also present in injection mixes (not shown). (B) Fluorescent thrombocyte binding and adhesion at 5 dpf were monitored for each experimental group over time after PCV laser injury. Each line represents the mean fluorescence (+/−SEM). The number of larvae per group is shown in brackets.

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.