ZFIN Image: Warchol et al., 2021, Figure 2

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Figure 2

Macrophage response to neomycin ototoxicity. Images are maximum-intensity projections of confocal z-stacks of 15 μm depth. Uninjured neuromasts (“Control”) usually possess 1–2 adjacent macrophages (green). Macrophages enter the neuromasts in response to treatment in 100 μM neomycin. Images in the center and right show macrophages at 10 and 20 min of exposure to neomycin. Some macrophages (arrow, 10 min) extended processes that contact hair cells (red, otoferlin), while other macrophages had internalized the debris of dead hair cells (arrowhead, 20 min).

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Cell. Neurosci.