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Figure 2

ID: ZDB-IMAGE-210128-10
Publication: Warchol et al., 2021 - Macrophages Respond Rapidly to Ototoxic Injury of Lateral Line Hair Cells but Are Not Required for Hair Cell Regeneration
All Figures: Figures for Warchol et al., 2021

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Figure 2

Macrophage response to neomycin ototoxicity. Images are maximum-intensity projections of confocal z-stacks of 15 μm depth. Uninjured neuromasts (“Control”) usually possess 1–2 adjacent macrophages (green). Macrophages enter the neuromasts in response to treatment in 100 μM neomycin. Images in the center and right show macrophages at 10 and 20 min of exposure to neomycin. Some macrophages (arrow, 10 min) extended processes that contact hair cells (red, otoferlin), while other macrophages had internalized the debris of dead hair cells (arrowhead, 20 min).

Acknowledgments

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