ZFIN Image: Loontiens et al., 2020, Fig. 3

Image

Figure Caption

Fig. 3

PHF6 controls the expression of hematopoietic lineage genes. (A,B) Gene Set Enrichment Analysis shows that an early B cell gene signature is significantly enriched at expense of (A) a myeloid gene signature (GSE24759) and (B) NK cell (CD56⁺CD16⁺CD3^–) gene signature (GSE24759) in short-term cultures of CD34⁺ progenitors on an OP9-GFP stromal feeder layer with stable PHF6 knockdown (GSE85373). (C,D) Gene Set Enrichment Analysis shows that an erythrocyte gene signature (C) but not a MEP gene signature (D) is significantly enriched at expense of a HSCs gene signature (GSE24759) in short-term cultures of CD34⁺ progenitors on an OP9-GFP stromal feeder layer with stable PHF6 knockdown.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol