ZFIN Image: Zhang et al., 2020, Fig. 3

Image

Figure Caption

Fig. 3 Hypertrophic gonads of amh mutants at 4 mpf. (A) The mutant male individuals (amh−/−) showed enlarged abdomen and huge testes (arrows) when compared with the controls (amh+/+ and amh+/−). By comparison, no obvious difference was observed among different genotypes in females. (B) Dissected gonads and quantification of gonadal weight and GSI. *** P < 0.001. (C) Histological examination of testes from different genotypes (amh+/+, amh +/− and amh−/−). The mutant testis (amh−/−) contained much higher number of pre-meiotic spermatogonia (asterisks) but much less meiotic spermatocytes (SC) and post-meiotic mature spermatozoa (SZ).

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Phenotype details

Acknowledgments

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Reprinted from Molecular and Cellular Endocrinology, 517, Zhang, Z., Zhu, B., Chen, W., Ge, W., Anti-Müllerian hormone (Amh/amh) plays dual roles in maintaining gonadal homeostasis and gametogenesis in zebrafish, 110963, Copyright (2020) with permission from Elsevier. Full text @ Mol. Cell. Endocrinol.