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Figure 1 (A) Comparison of three major orthology databases with the BigWenDB. The relative contribution of four metazoan clades (Deuterostomia, Ecdysozoa, Lophotrochozoa, and the paraphyletic group "non-Bilateria") is shown as stacked bar graph. The count of metazoans in our database (175 species) is set to 100%. In comparison to other databases, the BigWenDB has a larger repertoire of critical lophotrochozoans and non-bilaterian Metazoa. (B) Consensus phylogeny describing the relationships of 21 metazoan phyla covered in our database, after Laumer et al., 2015; Telford et al., 2015; Torruella et al., 2015; Cannon et al., 2016. Bold labels to the left or above branches indicate its ancestor (A: Arthropoda, B: Bilateria, D: Deuterostomia, E: Ecdysozoa, Eu: Eumetazoa, L: Lophotrochozoa, M: Metazoa, O: Opisthokonta, P: Protostomia). Numbers in parentheses (after the phylum name) indicate the number of species present from this phylum. Horizontal bars visualise the number of database sequences that belong to a given phylum (logarithmic scale; transcriptomic, ORF, and NCBI sequences summed up). Species silhouettes were downloaded from www.phylopic.org. Morphological innovations of Bilateria according to Baguñà et al., 2008 are highlighted in a shaded box.