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Fig. 2.

ID: ZDB-IMAGE-200910-14
Publication: Spinazzola et al., 2020 - Effect of serotonin modulation on dystrophin-deficient zebrafish
All Figures: Figures for Spinazzola et al., 2020

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Fig. 2.

Short-term assay of serotonin, serotonin precursors, products and receptor agonists. (A–E) Treatment with serotonin, 5-hydroxy-L-tryptophan (5-HTP), tryptophan, melatonin and cisapride did not significantly decrease the percentage of zebrafish exhibiting the affected muscle phenotype detected by birefringence. Treatment with 2.5 μg/ml aminophylline significantly decreased the percentage of affected fish. Data represent means±s.e.m.; *P<0.05 versus paired control by one-way ANOVA and Bonferroni post-hoc test. Values above each column indicate the number of sapje (N) and sapje-like (n) fish treated with the respective drug. (F) Both affected and unaffected zebrafish treated with ≤16.5 μM cisapride exhibited abnormal body morphology.

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Phenotype details

Acknowledgments

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