ZFIN Image: Zhou et al., 2019, Fig. 2

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Figure Caption

Fig. 2

Timo AIII inhibits ISVs growth in zebrafish. a Transgenic zebrafish Tg(fli-1a: EGFP)^y1 expressed EGFP in endothelial cells, and the vessels were easily observed under a microscope. Twenty-four hpf (hour post fertilization) zebrafish embryos were treated with various concentrations of Timo AIII (0.5, 1, 2, and 3 µM) for 12 h and then imaged under an inverted microscope. Red asterisks indicate defective ISVs. b The statistical graph indicates the intact and defective vessel numbers of ISVs in zebrafish. The results are presented as the means ± S.E.M. *P < 0.05 and ***P < 0.001 versus the control group

Acknowledgments

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