Zebrafish cq96 mutants display aberrant liver maturation. The liver was labeled by Tg(lfabp:Dendra2-NTR)cq1. A, bright field and green fluorescence image of WT and cq96 mutant at 5 dpf showing the morphology and liver fluorescence expression. B, confocal images of WT and cq96 at 5 dpf revealing the liver size and morphology. C, whole-mount in situ hybridization (WISH) results showing the expressions of trypsin, ifabp, and cp in WT and cq96 mutant at 5 dpf. D, evaluating the liver function by WISH results of uox and gc in WT and cq96 mutant at 5 dpf. BF, bright field. Numbers indicate the proportion of larvae exhibiting the expression shown. Scale bars, 100 μm.
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Full text @ J. Biol. Chem.
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