ZFIN Image: Chen et al., 2020, Figure 3

Image

Figure Caption

Figure 3

UVB activates p53 and DNA damage in zebrafish. Embryos aged 3 dpf were irradiated with UVB (+UVB) at a dose of 300 J/m². Twenty-four hours later, the irradiated embryos were fixed and stained with p53, Ku80, and Rad51 antibodies. Embryos without (A–C) or with UVB irradiation (D–F) were stained with p53 (green) and Hoechst (purple) antibodies and detected under high-resolution confocal microscopy. The p53 protein translocated to the nucleus of cells undergoing apoptosis at 19 h after 300 J/m² UVB irradiation.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Animals (Basel)