ZFIN Image: Zhang et al., 2020, FIGURE 5

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Figure Caption

FIGURE 5

lncRNA NR2F1‐AS1 promotes breast cancer angiogenesis via IGF‐1/IGF‐1R/ERK pathway. A, GO enrichment of the target genes of miRNA‐338‐3p. B, KEGG analysis of the target genes of miRNA‐338‐3p. C, Pearson's correlation analysis of lncRNA NR2F1‐AS1 and IGF‐1. D, Dual‐luciferase reporter gene assay of miRNA‐338‐3p and IGF‐1. E, Protein expression of IGF‐1 in transfected MDA‐MB‐231 and MCF‐7 cells (representative image) and the Western blot analysis. F, Phosphorylation of IGF‐1R and ERK1/2 in HUVECs cultivated in TCM from transfected breast cancer cells (representative image) and the Western blot analysis. *P < .05; **P < .01; ***P < .001; ****P < .0001

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