Immune reconstitution responses after chemotherapy illustrated in histological sections of a human BU lesion (from Schütte et al., 2007) and in a sketch of the participating immune components (created with biorender.com). Three main types of cellular infiltration have been observed in BU patients after treatment with the standard antibiotic regimen, including diffuse, heterogeneous cellular infiltration of the connective and adipose tissue (100× magnified) (A), granuloma-like structures in the connective tissue (40× magnified) (B), and follicle-like lymphocyte structures adjacent to vessels (40× magnified) (C).
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