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ID: ZDB-IMAGE-200406-190
Publication: Pei et al., 2020 - A subset of SMN complex members have a specific role in tissue regeneration via ERBB pathway-mediated proliferation
All Figures: Figures for Pei et al., 2020

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Figure Caption

Fig. 1 Hair cell regeneration analysis for mutations in each gene of the SMN complex.

Hair cell regeneration is impaired by homozygous mutations of gemin3^hg105a, smn1^hg104b, and gemin5^hg107c, but not in gemin2^hg108d, gemin4^hg109e, gemin6^hg110f, gemin7^hg111g, gemin8^hg112h, or strap^hg113i. Red line separates the mutations impacting regeneration from those that have no effect on regeneration. wt wild-type, het heterozygotes, hom homozygotes. Error bars in the graphs represent mean ± s.e.m. The difference between wild-type and homozygote is labeled. ns, P > 0.05; ***P < 0.001; ****P < 0.0001. Approximately 40 embryos were used for each of the regeneration analyses and then genotyped to study the genotype–phenotype correlation.

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Phenotype details

Acknowledgments

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