ZFIN Image: Contreras et al., 2020, Figure 10

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Figure Caption

Figure 10

Proposed mechanisms triggering the AGS. (A) Mechanisms mediated by CD4⁺ T cells or T helper (T_H) cells that develop into T_H1 and T_H2 cells regulating cell-mediated and antibody-mediated innate and adaptive immune responses, respectively. (B–D) Immune mechanisms triggering the AGS that have been proposed based on existing evidence in (B) humans, (C) α1,3-GalT-KO mice, and (D) our zebrafish animal model. The interrogation marks (?) represent mechanisms that need additional evidence to be sustained.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Infect Microbiol