ZFIN Image: L et al., 2020, Figure 5

Image

Figure Caption

Figure 5

Effects of ZnO-NPs on caspase cascade in human GSCC cells. Ca9-22 cells were treated with the indicated concentrations of ZnO-NPs for 24 h. Then, cells were harvested and lysed for the detection of initiator caspase (caspase -8 and -9) (a), caspase-3, and poly-(ADP-ribose) polymerase (PARP) (b) by Western blot analysis. (c) The quantitative densitometry of cleaved form of the indicated caspases and PARP was performed with Image-Pro Plus. (d) Percentage cell viability assessed by MTT assay in GSCC cells, which were treated with ZnO-NPs in the presence or absence of Z-VAD-FAK. Data represent the mean ± SEM of three independent experiments. * p < 0.05 compared with the control group, # p < 0.05 compared to ZnO-NP-treated cells.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.