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Figure 1
Strategy for creating bioinspired molecular factories. To create a molecular factory (MF) we start by internalizing artificial cargoes (specific molecules and preformed artificial organelles based on polymersomes loaded with active compounds) in the donor mammalian cell. The membrane of the donor cell can also be modified to contain proteins or receptors of interest. Once loaded with all the necessary components of the MF, a transfer of material from the donor cell cytoplasm and membrane is achieved during vesicle formation. After isolation, the MFs are completely independent of the donor cells.
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Full text @ Adv Sci (Weinh)