IMAGE

Fig. 7.

ID

ZDB-IMAGE-200205-13

Genes

d2EGFP

Publication

Clark et al., 2019 - Establishment and validation of an endoplasmic reticulum stress reporter to monitor zebrafish ATF6 activity in development and disease

All Figures

Figures for Clark et al., 2019

Image

Figure Caption

Fig. 7.

Heat shock activates reporter expression. (A) Representative images showing increased 5XATF6RE:d2GFP expression in the spinal cord 8 h after heat shock compared to a control without heat shock. (B) Representative images and quantification of the lens (indicated by an arrow) revealed significantly higher levels of 5XATF6RE:d2GFP expression 2 days post-heat shock compared to a control without heat shock (P<0.0001). The dashed line outlines the eye. (C) Representative images and quantification of the head region (dashed line) revealed significantly higher levels of 5XATF6RE:d2GFP expression 12 h post-heat shock compared to a control without heat shock (P=0.0248). *P≤0.05; ****P≤0.0001; unpaired Student's t-test. All error bars are s.e.m. Scale bars: 0.1 mm (A,B); 1 mm (C).

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.