ZFIN Image: Fernando et al., 2019, Figure 3

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Figure 3

IPA inhibits the proliferation of EA.hy926 cells. (A) Cytotoxicity of IPA in EA.hy926 cells. The cells were treated with different IPA concentrations (0, 0.05, 0.15, 0.5, 1.5, and 2.5 µM) for 24 h, and the cell viability was determined by 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The results were normalized to blank (0 µM IPA). (B) IPA inhibits the proliferation of high glucose-induced EA.hy926 cells. The cells were treated with different concentrations of IPA (0.05, 0.15, 0.5, and 1.5 µM), along with 30 mM glucose. MTT assay was performed to determine cell viability. The anti-proliferative effects of IPA in high glucose-induced cells were normalized to C (control (30 mM glucose + 0 µM IPA)), and the effects of 30 mM glucose were compared to B (blank (0 mM glucose + 0 µM IPA)). ns; not significant, * p ˂ 0.05, ** p ˂ 0.01, *** p ˂ 0.001, ^##p ˂ 0.01.

Acknowledgments

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