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Figure 6

ID: ZDB-IMAGE-191230-397
Publication: Duan et al., 2019 - Exosomal miR-17-5p promotes angiogenesis in nasopharyngeal carcinoma via targeting BAMBI
All Figures: Figures for Duan et al., 2019

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Figure 6

miR-17-5p targeted BAMBI expression and regulated AKT/VEGF-A signaling. A: Wild-type miR-17-5p target sequences of BAMBI mRNA 3'-UTR. Using luciferase reporter assays to quantitatively detect the relative luciferase activities of wild-type and mutant. (B-D): Quantifications of BAMBI mRNA and protein level in HUVECs using Real-time PCR and western blot. E: Real-time PCR detected BAMBI expression in HUVECs incubated with CNE-2 derived exosomes. F: Human VEGF-A Precoated ELISA Kit was used to measure serum VEGF-A levels in 6 NPC patients and 6 healthy controls. G: Western blot of BAMBI, p-AKT, AKT and VEGF-A expression in HUVECs. β-actin as the loading control. The data shown were representative of at least three independent experiments. * p < 0.05. ** p< 0.01.

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