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Figure 5

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Publication: Duan et al., 2019 - Exosomal miR-17-5p promotes angiogenesis in nasopharyngeal carcinoma via targeting BAMBI
All Figures: Figures for Duan et al., 2019

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Figure 5

HUVECs ingested NPC derived exosomal miR-17-5p to promote angiogenesis. A: Real-time PCR analysed miR-17-5p expression in HUVECs which was co-cultured with CM from CNE-2 cells. B: Representative electron microscopy image of exosomes. C: Western blot showed the level of different kinds proteins in exosomes and CNE-2 cells. Flotillin-1 was the loading control. D: MiR-17-5p expression in exosomes was detected by Real-time PCR. E: Confocal microscopy images showed the ingestion of PKH67-labeled exosomes by HUVECs. Hoechst stained the nuclei (blue) and PKH67 labeled the exosomes (green). F: Real-time PCR showed miR-17-5p expression in HUVECs after absorbed exosomes from CNE-2 cells. (G-H): Morphology of SIVs in 5 dpf Tg(fli1a:EGFP) embryos injected with CNE-2 derived exosomes.

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