ZFIN Image: Li et al., 2019, Fig. S7

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Figure Caption

Fig. S7

Injection of bmp4 MO and bmp7a MO efficiently leads to developmental defects.

(A-B) Knockdown of bmp4 perturbed asymmetrical left-right patterning. Tg(cmlc2:EGFP)embryos was injected with ng bmp4 MO at one-cell stage. Defects in cardiac jogging was visualized by EGFP expression at 30 hpf. Different types of EGFP expression fluorescence in the heart were shown in ventral views (A). The ratios were shown in (B). Scale bars, 50 μm. (C-D) Knockdown of bmp7a resulted in a range of dorsalized phenotypes. Wild-type embryos were injected with ng bmp7a MO at the one-cell stage and imaged at 36 hpf. Representative dorsalized morphologies (C1-C3) are shown in (C) and their ratios are shown in (D). Scale bar, 100 μm.

Acknowledgments

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