ZFIN Image: Talbot et al., 2019, Fig. 6

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Figure Caption

Fig. 6

Smo function is required during migration for AbFM/AdFM partitioning. (A-D) Confocal projections of six1b:lyn-GFP (green) and mylpfa:mCherry (magenta) transgene expression in embryos fixed at 36 hpf (A,B) or 48 hpf (C,D). When embryos are treated with cyclopamine beginning at 24 hpf, fin buds form and become populated with MMPs; however, few MMPs contribute to the AbFM. At 36 hpf (A,B), we show an individual confocal plane (inset) that highlights defective AbFM/AdFM partitioning. (E,F) Embryos treated with cyclopamine from 24-36 hpf conspicuously lack hgfa expression in the fin bud domain (green arrows). Arrowheads are as described in Fig. 1 legend. Scale bars: 100 µm.

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Acknowledgments

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