Image
|
Figure Caption
Figure 6
Effect of the mTOR inhibitor rapamycin on the DNR-driven expression of luciferase in HEK293 cells. The effects on the empty vector and the two 11 (WT) and 13 (Risk) DNR alleles are shown for a range of rapamycin concentrations. Rapamycin decreases luciferase activity for both alleles and reaches a plateau after ~30 nM. At this concentration the difference between the two alleles is no longer significant.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ G3 (Bethesda)