ZFIN Image: Pickett et al., 2018, Fig. 5-S1

Image

Figure Caption

Fig. 5-S1

Reduced hair cell activity does not influence hair cell turnover.

Maximum projects of (A) DMSO control and (B) benzamil-treated fish expressing hair cell-specific membrane GFP (Tg[Pou4f3:gap43-GFP]) and photoconverted, nuclear localized EOS (Tg[Atoh1a:nls-Eos]^w214) at 5dpf. (C) The ratio of red label-retaining hair cells to total number of hair cells per neuromast counted at 5dpf. There is no difference between control and treated groups, indicating that reduced MET does not lead to increased hair cell turnover. Control: 0.72 ± 0.12, n = 8 control fish; Treated: 0.70 ± 0.14, mean ratio ±SD, n = 10 fish; 2–3 neuromasts analyzed per fish; Mann-Whitney U test, p = 0.76. Asterisks indicate hair cells with label-retaining nuclei. Scale bar = 5 μm.

Figure Data

Expression / Labeling details

Acknowledgments

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