ZFIN Image: Chrispell et al., 2018, Fig. 4

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Figure Caption

Fig. 4 Recovery of the isolated cone-mass receptor potential to successive stimuli. (A) Representative ERG waveforms of APB-treated, dark-adapted larvae subjected to successive stimuli using a dual flash paradigm of a 20-ms flash of saturating white light (1000 cd/m²) with an interstimulus interval (ISI) of 2 s. Vertical black dotted lines indicate time of stimulus. (B) Data are plotted as the ratio of the maximum isolated cone mass receptor potential response of the second stimulus to that of the initial stimulus for ISIs ranging from 0.75 s to 5 s. A linear mixed model analysis of covariance found a significant effect of genotype when compared to wildtype for grk1b^−/− (F_[1,49] = 6.5; P = 0.0142) and grk7a^−/− (F_[1,33] = 36.6; P < 0.001). Inset, regression to the logarithmic linear part of the recovery kinetics.^{[ref. 7]} Error bars represent SEM.

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Phenotype details

Acknowledgments

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