Fig. 6
- ID
- ZDB-IMAGE-180907-7
- Publication
- Powell et al., 2017 - Chemokine Signaling and the Regulation of Bidirectional Leukocyte Migration in Interstitial Tissues
- All Figures
- Figures for Powell et al., 2017
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Fig. 6
Cxcl8a Is Required for Neutrophil Reverse Migration from the Wound
(A) Average number of neutrophils at the wound is compared in WT, cxcr1−/−, cxcr2−/−, and cxcl8a−/− larvae (n = 13–32 larvae per time point/condition).
(B) Sudan black staining of neutrophils at 3 and 6 hpw in WT and cxcl8a−/−.
(C) Quantification of neutrophils at the wound shows more neutrophils at 6 hpw in cxcl8a−/− compared to heterozygote siblings (n = 74 WT and 75 mutants [3 hpw] and 91 WT and 70 mutants [6 hpw]).
(D) Representative tracks of neutrophils at the wound in cxcl8a+/− and cxcl8a−/− larvae.
(E) Neutrophil duration at the wound is greater in cxcl8a−/− than in heterozygotes (n = 17 het and 15 mutant larvae).
(F) Meandering index is decreased in cxcl8a−/− compared to het siblings. ∗p < 0.05.
Error bars represent SE.