ZFIN Image: Janjuha et al., 2018, Fig. 3-S1

Image

Figure Caption

Fig. 3-S1

Activation of NF-kB signaling in beta-cells of the secondary islets with age.

(a,b,c) Confocal stack of secondary islets from Tg(NF-kB:GFP) animals at 1 mpf, 3 mpf and 1 ypf. Beta-cells were labeled using an insulin antibody (red). NF-kB:GFP reporter expression is shown in green. Scale bars 20 µm. (a’,b’,c’) Insets show high-magnification single planes of the confocal stacks corresponding to the regions outlined using white dotted-lines in the top panels. Scale bar 10 µm. (d) Graph showing the total normalized GFP fluorescence intensity of the secondary islets from 3 mpf (n = 9 fish, secondary islets = 32) and 1 ypf (n = 8, secondary islets = 30) animals. Each dot represents one islet (two-tailed t-test, *p<0.05).

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Elife