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Fig. 2
Formin antagonism induces craniofacial defects in developing zebrafish embryos. (A) Representative 2x images at 21 hpt untreated (None) and in 10 μM SMIFH2. (B–D) Craniofacial defects were scored for embryos in each untreated, vehicle, and SMIFH2 (B), IMM (C), and PEG-DAD (D) drug conditions. The screens were performed in triplicate, five embryos/well and the experiment was repeated three times. Values are represented as % expressing squared faces per condition. p- value is relative to untreated condition. Error bars indicate SE. Scale bars = 2,000 μm.
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