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Fig. S6
Flow profiles around (and close to) arrested tumor cells in the zebrafish embryo. (A) Scheme depicting flow profiles around arrested TC in the zebrafish embryo (Open, partially clogged and clogged) and quantification of the distance between arrested TC and the first fully perfused vessel (B) Images of in silico simulations for the respective scenario (C) Images and analysis of high-speed confocal acquisitions in the zebrafish embryo. Values in (A) are mean ±SD.
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Reprinted from Developmental Cell, 45, Follain, G., Osmani, N., Azevedo, A.S., Allio, G., Mercier, L., Karreman, M.A., Solecki, G., Garcia Leòn, M.J., Lefebvre, O., Fekonja, N., Hille, C., Chabannes, V., Dollé, G., Metivet, T., Hovsepian, F., Prudhomme, C., Pichot, A., Paul, N., Carapito, R., Bahram, S., Ruthensteiner, B., Kemmling, A., Siemonsen, S., Schneider, T., Fiehler, J., Glatzel, M., Winkler, F., Schwab, Y., Pantel, K., Harlepp, S., Goetz, J.G., Hemodynamic Forces Tune the Arrest, Adhesion, and Extravasation of Circulating Tumor Cells, 33-52.e12, Copyright (2018) with permission from Elsevier. Full text @ Dev. Cell