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Fig. 5
BMP6-induced cluster phenotype in MDA-MB-231 cell invasion.
(a) qPCR analysis showing the BMP6 mRNA expression in MCF10A M2 and MDA-MB-231 cells. (b,c) Representative images of typical ‘single-cell’ invasion (b) and ‘cluster’ invasion (c) phenotype after BMP6 pre-treatment. (d) representation of the percentage of negative, cluster and single cell invasion phenotypes in zebrafish larvae injected with control and BMP6 pre-treated MDA-MB-231 cells. Scale bar: 100 μm. *0.01 < P < 0.05.
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