IMAGE

Fig. 5

ID

ZDB-IMAGE-171101-45

Genes

neurog1

Publication

Cheng et al., 2015 - Deltex1 is inhibited by the Notch-Hairy/E(Spl) signaling pathway and induces neuronal and glial differentiation

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Figures for Cheng et al., 2015

Image

Figure Caption

Fig. 5

Disruption of Dtx1 expression by using dtx1 ^ΔIII or dtx1 morpholino reduces neuronal differentiation. a The injection of dtx1 ^ΔIII or dtx1 morpholino caused an identical phenotype, which downregulated neurog1 (a) and HuC/D expression (b) The phenotypes caused by the morpholino injection could be rescued by a concomitant injection of dtx1 ^full cRNA. The embryo stages are shown in the bottom left corner of each panel. c qPCR analysis confirmed the results obtained through in situ hybridization in a d Counting the HuC/D-positive cells confirmed the results obtained in b *, P < 0.05; **, P < 0.01; ***, P < 0.001

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

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