ZFIN Image: Leerberg et al., 2017, Fig. S1

Image

Figure Caption

Fig. S1

A fraction of fgf24 mutants undergo latent testis development.

(A-B) Dissected testes from 3.5 mpf wild-type (WT; A) and fgf24 mutant (B) animals, anterior to the left. (C, D) Confocal images of isolated Tg(ziwi:EGFP) (green) and DAPI (blue) stained 4 mpf wild-type (C) and mutant (D) testes. Sg = spermatogonia; Sc = spermatocytes; Sz = mature spermatozoa; Sgc = somatic gonad cells. (E-H) in situ hybridization showing expression of amh (E, F) and gsdf (G, H) in 6 mpf wild-type (E, G) and mutant (F, H) testes. (I) Schematic diagram of the full-length Fgf24 protein and the predicted truncated peptides resulting from the fgf24^hx118 and fgf24^uc47 alleles. SP = signal peptide; hatching indicates missense amino acids. Scale bars = 20 μm.

Acknowledgments

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